Size | 48T |
Size | 96T |
Human HCV (Hepatitis C Virus) ELISA Kit Basic Information
Name | Human HCV (Hepatitis C Virus) ELISA Kit |
Catalog NO. | FY-EH4416 |
Detection Method | Qualitative |
Application | HCV ELISA Kit allows for the in vitro quantitative determination of HCV concentrations in serum, plasma, tissue homogenates and other biological fluids. |
Size | 48T, 96T |
Storage | 2-8 â for 6 months |
Species | Human |
CV (%) | Intra-Assay: CV<8%Inter-Assay: CV<10% |
Note | For Research Use Only |
HCV (Hepatitis C Virus) Introduction
The hepatitis C virus (HCV) is a small (55â65 nm in size), enveloped, positive-sense single-stranded RNA virus of the family Flaviviridae. The hepatitis C virus is the cause of hepatitis C and some cancers such as liver cancer (hepatolar carcinoma, abbreviated HCC) and lymmas in humans.The hepatitis C virus particle consists of a lipid membrane envelope that is 55 to 65 nm in diameter. Two viral envelope glycoproteins, E1 and E2, are embedded in the lipid envelope. They take part in viral attachment and entry into the Within the envelope is an icosahedral core that is 33 to 40 nm in diameter. Inside the core is the RNA material of the virus. Identification of the origin of this virus has been difficult but genotypes 1 and 4 appear to share a common origin. A Bayesian analysis suggests that the major genotypes diverged about 300â400 years ago from the common ancestor virus. The minor genotypes diverged about 200 years ago from their major genotypes. All of the extant genotypes appear to have evolved from genotype 1 subtype 1b.A study of genotype 6 strains suggests an earlier date of evolution: approximately 1,100 to 1,350 years Before Present. The estimated rate of mutation was 1.8 Ã 10â4. An experimental study estimated the mutation rate at 2.5â2.9 Ã 10â3 base substitutions per site per year.This genotype may be the ancestor of the other genotypes.
Reference:
1, "Hepacivirus C". National Center for Biotechnology Information (NCBI). Retrieved 3 January 2022.
2, Smith, Donald B.; et al. (23 June 2016). "Create 13 new species in the genus Hepacivirusand rename 1 species (family Flaviviridae)" (PDF). International Committee on Taxonomy of Viruses (ICTV). Retrieved 13 March 2019.