FY-EH11595 Human Interleukin 1 Receptor Like Protein 1 (IL1RL1) ELISA kit

Interleukin 1 Receptor Like Protein 1 (IL1RL1) Basic informationInterleukin 1 receptor-like 1, also known as IL1RL1 and ST2, is a protein that in humans is encoded by the IL1RL1 gene.ST2 is a member of the interleukin 1 receptor family. The ST2 protein has two isoforms and is directly implicated in the progression of cardiac disease: a soluble form (referred to as soluble ST2 or sST2) and a membrane-bound receptor form (referred to as the ST2 receptor or ST2L). When the myocardium is stretched, the ST2 gene is upregulated, increasing the concentration of circulating soluble ST2.The ligand for ST2 is the cytokine Interleukin-33(IL-33). Binding of IL-33 to the ST2 receptor, in response to cardiac disease or injury, such as an ischemic event, elicits a cardioprotective effect resulting in preserved cardiac function. This cardioprotective IL-33 rbalanced by the level of soluble ST2, which binds IL-33 and makes it unavailable to the ST2 receptor for cardioprotective result, the heart is subjected to greater stress in the presence of high levels of soluble ST2.Human Interleukin 1 Receptor Like Protein 1 (IL1RL1) ELISA Kit test methodFeiyue’s Human Interleukin 1 Receptor Like Protein 1 (IL1RL1) Elisa kit is an ELISA reagent for detection of Neutrol elastase in serum, plasma, tissue homogenates and other biological fluids.This kit uses sandwich ELISA to detect the concentration of Human Interleukin 1 Receptor Like Protein 1 (IL1RL1), Human Interleukin 1 Receptor Like Protein 1 (IL1RL1) -specific monoclonal antibody has been pre-coated in the wells of the supplied microplate. Standard samples and controls are added to interact with the immobilized antibody. A sandwich complex is formed by an additional anti- Human Interleukin 1 Receptor Like Protein 1 (IL1RL1) antibody with HRP-Streptavidin. TMB solution is added to react with the sandwich for ming optical by microplate reader. The concentration of Human Interleukin 1 Receptor Like Protein 1 (IL1RL1) in the sample can be calculated by comparing the absorbance of the sample with the standard curve.