| Stock | Urolithin Powder |
| Purity | 99% |
| Quantity | 1000KG Urolithin A Powder |
| Buy Urolithin A Powder | Urolithin A Powder Factory |
| Urolithin A Powder Supplement | Urolithin effects |
| Urolithin A benefits | Urolithin a side effects |
| Name | Urolithin A Powder |
| CAS | 1143-70-0 |
| Purity | 98% |
| Chemical name | 3,8-Dihydroxybenzo[c]chromen-6-one |
| Synonyms | 3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one; 3,8-DIHYDROXYDIBENZO-(B,D)PYRAN-6-ONE; 3, 8-Dihydroxy-6H-benzo[c]chromen-6-one; Castoreum pigment I; Urolithin A; 6H-Dibenzo(B,D)pyran-6-one, 3,8-dihydroxy-; 3,8-dihydroxy-6H-dibenzopyran-6-one); urolithin-A(UA;3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one |
| Molecular Formula | C13H8O4 |
| Molecular Weight | 228.2 |
| Melting Point | >300 °C |
| InChI Key | RIUPLDUFZCXCHM-UHFFFAOYSA-N |
| Form | solid |
| Appearance | Light Yellow powder |
| Half Life | |
| Solubility | Soluble in DMSO (3 mg/mL). |
| Storage Condition | Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Application | Urolithin A is a metabolite of ellagitannin; rmaceutical Intermediates |
| Testing Document | Available |
Urolithin A powder is a metabolite compound resulting from the transformation of ellagitannins by the gut bacteria and is an inducer of mitogy. Urolithin A shifts mitochondria from CI- to CII-driven respiration, extends lifespan and improves muscle function. It belongs to the class of organic compounds known as benzo-coumarins or dibenzo-α-pyrones. Its precursors – ellagic acids and ellagitannins – are ubiquitous in nature, including edible plants, such as pomegranates, strawberries, raspberries, and walnuts. Since the 2000s, urolithin A has been subject of preliminary studies regarding its possible biological effects.
Urolithin A powder can improve the quality and function of mitochondria, and increase the strength and endurance of aging muscles. It is the only natural product that has been proven to restart mitochondrial autogy and reverse muscle aging.
Urolithins are microflora human metabolites of dietary ellagic acid derivatives，such as ellagitannins. They are produced in the
human gut, and found in the urine in the form of urolithin B glucuronide after absorption of ellagitannins-containing food such as
pomegranate, strawberries, red raspberries, walnuts or oak-aged red wine.
During intestinal metabolism by bacteria, ellagitannins and punicalagins are converted to urolithins, which have unknown
biological activity in vivo in humans. Urolithins metabolites of pomegranate juice ellagitannins localize specifically in
the prostate gland, colon, and intestinal tissues of mice.
Ellagitannins exhibit low bioavailability and are transformed in the gut to ellagic acid and its microbiota metabolites.
Urolithins are found in plasma mostly as glucuronides at low concentrations.
Urolithins production is dependent on the gut microbiome enterotype. Individuals producing urolithins show a much higher abundance
of the Clostridium leptum group of Firmicutes lum than Bacteroides or Prevotella
In laboratory studies, urolithin A powder was shown to induce mitogy, which is a selective recycling of mitochondria by autogy, a process that cleans defective mitochondria following damage or stress, and tends to become less efficient during aging.[14] This effect has been observed in different animal species (mammalian , rodents and C. elegans).
Urolithin A powder is intended for use as an ingredient in select foods or for special dietary uses in meal replacement products based on its nutritive activity in supporting general mitochondrial health.
Urolithin A is not known to be found in any food. It forms as the result of transformation of ellagic acids and ellagitannins by the gut microflora in humans. Ellagic acid itself results from the hydrolysis of ellagitannins in the gut in the presence of water.[citation needed]
Sources of ellagitannins are: pomegranates, nuts, some berries (raspberries, strawberries, blackberries, cloudberries), tea, muscadine grapes, many tropical fruits, and oak-aged wines (table below).
The conversion of the ellagic acids into urolithin A depends on individual microflora composition and can vary significantly.
Signup today to claim your Discount. Get Started before it's too late!
