-018 is a mildly selective agonist of the periral cannabinoid (CB2) receptor, derived from the aminoalkylindole WIN 55,212-2. The Ki values for binding central cannabinoid (CB1) and CB2 receptors are 9.0 and 2.94 nM, respectively, for a CB1:CB2 ratio of 3.06.1 Its effects on suppression of spontaneous activity, maximum possible antinociceptive effect in the tail-flick assay, and rectal temperature are comparable to those of WIN 55,212-2 when tested in rats.
The Ki values for binding central cannabinoid (CB1) and CB2 receptors are 9.0 and 2.94 nM, respectively, for a CB1:CB2 ratio of 3.06.1 Its effects on suppression of spontaneous activity, maximum possible antinociceptive effect in the tail-flick assay, and rectal temperature are comparable to those of WIN 55,212-2 when tested in rats.
It is a research chemical that belongs to the nahoylindole family. -081 as all the other research chemicals in the group is a synthetic cannabinoid with analgesic effects. Its full chemical name is 4-methoxynahalen- 1-yl- (1-pentylindol- 3-yl)methanone with chemical formula is C25H25NO2 and molecular mass 371.47 g/mol.
Signup today to claim your Discount. Get Started before it's too late!
