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Nicotinamide adenine dinucleotide(NAD) powder (53-84-9)

  • Origin: China
  • Supply Type: in stock
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Nicotinamide adenine dinucleotide(NAD) powder (53-84-9)
NAD+ is an essential coenzyme required for life and lar functions. Enzymes are catalysts that make biochemical reactions possible. Coenzymes are ‘helper’ molecules that enzymes need in order to function.
Name β-Nicotinamide adenine dinucleotide (NAD) powder
CAS 53-84-9
EC 200-184-4
Purity 98%
Chemical name beta-Dispyridine nucleotide
Synonyms Cozymase, β-NAD, β-DPN, DPN, Dispyridine nucleotide, β-Nicotinamide adenine dinucleotide hydrate, NAD, Coenzyme 1, Nadide
Molecular Formula C21H27N7O14P2
Molecular Weight 663.4 g/mol
Melting Point 160 °C (320 °F; 433 K)
InChI Key BAWFJGJZGIEFAR-NNYOXOHSSA-N
Form Solid (lyolized or crystaler)
Appearance White powder
Solubility Soluble in water (100 g/l) at 20° C.
Use Cosmetic,Dietary Supplement,IVD ,biocatalysis (enzymatic synthesis)
Testing Document Available
Bulk Density 1.5-7g/ml
Particle size >80 mesh
Storage Condition Keep dry ,away from light, and store at 2℃- 8℃, long term store at -15℃ to -25℃
Package 10gram/bag ,50gram/bag , 1KG/bag, 25KG/drum
Application β-Nicotinamide adenine dinucleotide (NAD+) and β-Nicotinamide adenine dinucleotide, reduced (NADH) comprise a coenzyme redox pair (NAD+:NADH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. In addition to its redox function, NAD+/NADH is a donor of ADP-ribose units in ADP-ribosylaton (ADP-ribosyltransferases; poly(ADP-ribose) polymerases ) reactions and a precursor of cyclic ADP-ribose (ADP-ribosyl cyclases).
Greener alternative product characteristics Waste Prevention
Less Hazardous Chemical Syntheses
Safer Solvents and Auxiliaries
Design for Energy Efficiency
Use of Renewable Feedstocks
Inherently Safer Chemistry for Accident Prevention
Learn more about the Principles of Green Chemistry.
DESCRIPTION
General description
Nicotinamide adenine dinucleotide (NAD) is a cofactor containing an adenylic acid and a nicotinamide-5′-ribonucleotide group linked together by a pyroste moiety. It is ubiquitously found. In NAD+ complexes, the enzyme-cofactor interactions are highly conserved.
Application
NAD has been used in boiled-blood agar plate as a supplement for the growth of Actinobacillus pleuropneumoniae colony.
Biochem/siol Actions
Nicotinamide adenine dinucleotide (NAD) acts as an electron carrier and significantly participates in enzyme-catalyzed oxido-reduction processes and many genetic processes. NAD cycles between the oxidized (NAD+) and reduced (NADH) forms to maintain a redox balance necessary for continued growth. This cofactor is also involved in microbial catabolism. β-NAD acts as a substrate for various enzymes in several lar processes.
Electron acceptor
Packaging
Packaged by solid weight.
Quality
Absence of contaminants: LDH inhibitors are not detectable.
Organic solvents: <0.5% (GC)
Preparation Note
Storage conditions (working solution): An aqueous solution in a concentration of 10 mg/ml (2.5 to 3) maintains > 99% of its NAD content after 8 weeks of storage at 2 to 8 °C. The stability of an aqueous solution in a concentration of 40 mg/ml is not expected to differ from that of a solution in a concentration of 10 mg/ml. An aqueous solution in a concentration of 50 mg/ml (2.0) maintains 97% of its NAD content after 2 days, 94% after 6 days and 91% after 10 days of storage at 2 to 8 °C and about 83% after 10 days of storage at 33 °C. An aqueous solution in a concentration of 1.38 mg/ml shows a decrease of NAD content of 4% after 8 weeks of storage at 2 to 8 °C, stored at -15 to -25 °C the stability is expected to be > 6 months. A solution of NAD in triethanolamine buffer (5.0) maintians 90% of its NAD content after 10 days of storage at 2 to 8 °C and 80% after 10 days of storage at 33 °C.
Analysis Note
ß-Nicotinamide adenine dinucleotide hydrate cofactor (NAD) has been used in an experimental protocol, done in order to mimic the citric acid cycle on an carbon electrode, in order to increase biofuel energy density.
Absorbance coefficients: 17.6 x 103 l x mol-1 x cm-1 at 260 nm, 5.9 x 103 l x mol-1 x cm-1 at 333 nm (CN complex)
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