Storage instructionsStore at -20℃. Avoid freeze / thaw cycles.
Storage bufferPBS with 0.05% sodium azide, 50% glycerol, .3
BackgroundThis gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic . The Knops blood group system is a system of antigens located on this protein. The protein mediates lar binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomeruloneitis, systemic lupus erythematosus and sarcoidosis.
